Dodecyl Nitrile (Clonal)

CAS : 2437-25-4
Fragrance profile : Dry citrus, orange peel, metallic, spicy, with a subtle waxy and rosey undertone
Appearance : Clear liquid from colourless to light yellow/orange
Fragrance strength : medium
Fragrance duration : 240 hours on fragrance strip
Fragrance group : citrus metallic
Molecular formula : C₁₂H₂₃N
Synonyms : lauronitrile; Clonal (IFF); Mandaryl; aldinyle 3881 (Synarome); Undecyl cyanide (obsolete name)

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What is dodecyl nitrile?

A 12-carbon long chain nitrile that has a metallic, citrusy, and spicy odor. In perfumery, the name dodecyl nitrile is usually used because of its recognizability and odor association.

  • Chemical Structure : It is a nitrile compound with a long carbon chain (12 carbon atoms), which gives it a soft, skin-like scent.
  • Fragrance Character : Dodecyl nitrile is known for its metallic, musky, and skin-like scent , often described as synthetic yet warm and sensual.
  • Application : Widely used in modern perfumery to create a clean, abstract, and sometimes slightly sweaty effect — especially in niche fragrances or avant-garde perfumery.

In perfumes

Dodecyl nitrile is often combined with:

  • Aldehydes for a fresh, sparkling opening
  • Musk notes for a soft, skin-like base
  • Green or citrus notes to balance the metallic character

 

Fragrance application

  • Fragrance type : Citrusy, with a metallic and spicy undertone .
  • Uses : Used as a fragrance-diffusing agent in soap perfumes and as a top note modifier , especially when aldehydes, woody notes, or green notes are dominant.
  • Do not confuse with : Dodecanal (Aldehyde C-12) , which has a different odor profile

Dodecyl nitrile differs from other nitriles mainly due to its long carbon chain and its specific fragrance profile, which makes it particularly suitable for use in perfumery.

Structural differences

  • Dodecyl nitrile has a C12 chain (12 carbon atoms), which gives it a fatty, waxy, and skin-like odor .
  • Shorter nitriles such as acetonitrile (C2) or butyronitrile (C4) are much more volatile and have a sharper, more chemical odor — often not suitable for perfumery.
  • Longer chains such as octanitrile (C8) or lauronitrile (C12, same as dodecyl nitrile) have a softer, muskier scent.

 

Scent differences

Nitrile Carbon chain Fragrance profile Use in perfumery
Acetonitrile C2 Sharp, ethereal Industrial, no odor
Butyronitrile C4 Light fruity, chemical Limited
Benzonitrile Aromatic Bitter, almond-like Specific niche fragrances
Dodecyl nitrile C12 Citrusy, metallic, skin-like Widely applicable

 

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