Ambretone (Takasago) AC
Character: powerful, sweet, powdery, slightly animalic, ambery
CAS No.: 37609-25-9
Fragrance Group: Musk
Chemical name: (5Z)-cyclohexadec-5-en-1-one
Appearance: Solid, slightly powdery or waxy
Stability: very substantive, stays on a fragrance strip for a long time (>400 hours)
Dosage: usually in low doses 0.1 – 2% to give a musky base.
Use: as a base note in perfumes for long-lasting fixation; adds depth and senuality to floral, amber and musk compositions
IFRA: no restriction (Cat.4)

Ambretone – modern musk, luxurious, powdery and irresistible.
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Ambretone is like a whisper of luxury on your skin – powdery, warm, and endlessly elegant.
Ambretone by Takasago is a macrocyclic musk with exceptional substantivity and a luxurious, powdery softness.
It is distinguished by its exceptional diffusion and luxurious texture, making it a favorite ingredient of perfumers seeking a sophisticated musk with a touch of animalic warmth.
It adds a velvety, powdery dimension that transforms a composition from simple to opulent and complex.
Fragrance profile
- Main character: intense powdery musk
- Nuances: soft animalic, ambery, with a velvety roundness
- Comparison: reminiscent of classic nitro-musks, but cleaner and more modern
Use in perfumery
- Base note/fixative: Ambretone is a macrocyclic musk that anchors a perfume for a long time.
- Character: powdery, soft-animalic, ambery, luxurious.
- Combinations: works particularly well with floral accords (rose, iris, jasmine), amber notes and woods.
- Application: both in fine fragrance (perfumes, eau de parfum) and in cosmetics and detergents due to its stability and substantivity.
- Stability: good resistance to heat and light, making it widely applicable in various product types.
💡 Tips
- Dosage: in practice 0.1-2% often sufficient to give a perfume a luxurious musk body.
- Layering: combine with lighter musks (such as Galaxolide or Habanolide) to create a complex musk bouquet.
- Balance: use Ambretone to give floral accords more sensuality without making them too heavy.
Main related musks
| Name | Type | Fragrance profile | Particulars |
|---|---|---|---|
| Velvione | Macrocyclic musk | Powdery, soft, amber | Close relative of Ambretone; often used as an alternative |
| Muscenone | Macrocyclic musk | Sweet, fruity, slightly animalic | Very substantive, loved in fine fragrance |
| Exaltone | Macrocyclic musk | Warm, animalic, musky | Classic musk with high substantivity |
| Ambrettolide | Macrocyclic musk lactone | Sweet, fruity, floral | Natural association with ambrette seed |
| Habanolide | Macrocyclic musk | Metallic, fresh, clean musk | Gives modern, transparent musk feel |
| Helvetolide | Macrocyclic musk | Fruity, pear-like, musk | Popular in modern fruity perfumes |
| Romandolide | Macrocyclic musk | Clean, soft, musky | Transparent, skin-like effect |
| Ethylene Brassylate | Macrocyclic musk | Sweet, powdery, musky | Widely used in detergents and cosmetics |
| Galaxolide | Polycyclic musk | Clean, white musk | Very popular in consumer products |
Trivia
- Ambretone and Velvione are chemically closely related; Ambretone is often seen as the more luxurious, more powerful variety.
- Muscenone and Exaltone are classics that give a more animalistic musk tone.
- Ambrettolide is special because it is a lactone and adds a fruity-floral nuance.
- Habanolide and Helvetolide bring a modern, fresh and transparent musk feel, ideal for contemporary perfumes.
- Galaxolide and Ethylene Brassylate are more "white musks" and are widely used in mainstream perfumery and household products.
